Partners access


Welcome to the Centre for Studies and Research on integument * CERT

CERT is an informal structure situated within the Unit for Functional Exploration of Skin at Besançon hospital University (CHU) where clinical investigations are carried out. This centre provides expertise in the field of clinical studies and experimental work in vitro and ex vivo for partners. Composed of research engineers, research technicians, medical doctors, a librarian and an assistant manager, this team is capable of implementing clinical trials, biometrological methods with medical or cosmetic concern, pharmacological analysis, or cell biology studies. The studies which are conducted within the CERT, performed at the Besançon University Hospital, and are managed by the Inter Unec Association, which has framework agreement with the hospital. This partnership can contribute to basic research activities of Laboratory of Cutaneous Engineering and Biology (LIBC), University of Franche-Comté. By browsing this website, you will discover methods that will certainly interest in the evaluation of a molecule or a product. Always ready to listen the needs of the industrial world, and anxious to provide it with university resources and knowledge, the CERT has been, is, and, we hope, will be your partner. 5 keywords govern our mission: Creativity, Innovation, Professionalism, Discipline, and finally Satisfaction for our partners.


CERT Team (from left to right)

first row: A. Elkhyat, JM. Sainthillier, T. Lihoreau, P. Humbert, F. Fanian, C. Courderot

Second row : S. Mac-Mary, C. Viennet, A. Jeudy

Third row: C. Tarrit, P. Mermet, Y. Lboutounne, A. Durai, C. Thiébaut

* The integument is the envelop of the body, namely the skin, the mucosae and the skin appendages(hairs, nails…)
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
  • 9
  • 10
Prev Next

New publication with Thailand

In the frame of our collaboration with Phitsanulok university in Thailand, a new paper is published May 6th, 2017, on effect of natural extracts against UV alterations on skin cells: We had also the honor in these days to welcome...

Visit of Pr OH

Professor Chil Hwan Oh, M.D., Ph.D. came to visit our center on March 14th, 2017, and presented his works on molecular imaging. This visit reinfurces the relationships with the department of dermatology of Korea University (Seoul).

Solar lentigo

Following the PhD thesis of Mrs Ranesha Goorochurn ( ), a new research has been published  (February 17th, 2017) on solar lentigo:

Back on OCT in focus - Ausburg 2017

Back to the "OCT in focus" group last meeting: these researchers on skin imaging met again on 2017, January 21st in Ausburg, Germany; Dr. Fanian presented works of CERT concerning the applications of optical coherence tomography in aesthetic medicine and...

Keloid and bio engineering

In collaboration with the Center of Excellence for Molecular Imaging, Chiang Mai University (Thailand), a new publication has been accepted (January 17th, 2017), on 3D bio engineering of keloid scars:

100 questions about skin

Newspapers come back on the recent publication of a book written by Pr Humbert, about 100 questions about skin beauty and health (in french): Référence, MA Editions:

Melanoma - collaboration with Liege univ…

Collaboration with university of Liege, Belgium, and Pr Pierard, allows the publication of recent scientific articles: -PIERARD GE, NIZET JL, HUMBERT P Nouveaux paradigmes et métaphores du traitement du mélanome cutané Rev Med Liege 2016; 71 : 12 : 562-566. -PIERARD GE, PIERARD-FRANCHIMONT C, HUMBERT Ph,...

French book "Chimie, dermo-cosmétiq…

Pr Humbert participated in the writing of the french book "Chimie, dermo-cosmétique et beauté", published January 2017. ISBN : 978-2-7598-2077-1, 262 pages  

2017: happy new year!

The whole team of CERT wish you a very happy new year! The team also wishes to thank Vanessa Ecarnot for her work realized for 5 years, always with a great smile. She arrives as a training period student at CERT,...

Skin massages

General magazines also speak about the scientific studies carried out in CERT, here on the beneficial action of massages on the skin (in french):  The concerned clinical study results were published in a scientific journal in 2015:

Ferial Fanian is now PhD

Ferial FANIAN, MD, supported her PhD on December 14th, 2016.Conducted by Professor HUMBERT, her work focused on the relationship between cutaneous biometrology and biology, especially concerning pigmentation. The jury, chaired by Pr Christian CAVE, Pharm D, PhD at the University of Paris-Sud,...


CERT participated in the "Académie de Dermatologie Esthétique et Correctrice 2016", organized by the French Society of Dermatology ( and its thematic group gDEC (group of aesthetic and corrective dermatology). The event was held in Nantes on November, 17-18th. Thomas Lihoreau...

Shanghai collaboration

Pr Humbert was involved in a symposium in Shanghai, China, about "dynamic skin barrier and biometrology in skin care".It was the opportunity to reinforce and underline our collaboration with Skin Disease Hospital of Shanghai, and Dr Yuan Chao.

RCM and sensitive skin

CERT collaboration with Shanghai Skin Disease Hospital just produced a new paper on sensitive skin and its signs and follow-up thanks to Reflectance Confocal Microscopy method: 

Skin and pollution

CERT and Proviskin company ( share their skills to develop knowledges about the effects of pollution on the skin, including: - The effects of pollution on the penetration of active and ingredients;- The effects of pollution on the surface properties of...

OCT in focus 2016

Dr Ferial Fanian speaks on September 29th, 2016 at the "OCT in focus" meeting, held in Vienna. She presents the CERT researchs on non invasive imaging (and thus particularly Optical Coherence Tomography) for aesthetic medicine and cosmetology.  (have a look also at: )

Book on cosmetics evaluation

CERT participated in the writing of a book (published September 2016) on the objectification of cosmetic products, providing its expertise on the evaluation of the skin radiance:

GDR Cosm'actifs

CERT is part of GDR ("Groupe de Recherche) 3711 CNRS This group of researchers held a symposium on September 26-27th, 2016, at the Moulin d'Ande in Normandie, "At interface of science for cosmetics." Professor Philippe Humbert presented an overview of the...

CERT on french TV

Back on "Télématin" french TV program, in which CERT researches are mentionned, while Dermance anti-ageing products were presented (2010):  (CERT at 3'15)

Conference Pr Humbert - july 2016

Local newspaper talk about one of the conference of Pr Humbert, enhancing the importance and time to spend for diagnosis, for a better patient care. Est Républicain, July 23rd, 2016 (in french):

Design amenothès conception